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Vacation Rentals in Panama City

Find the vacation rentals that appeal to you the most

August 2026

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Find the right vacation rental for you in Panama City

The best vacation rentals in Panama City

Check out our selection of great vacation rentals in Panama City

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R.1110 Hermoso estudio ejecutivo, área turística.

Bella Vista, Panama City

R.1110 Hermoso estudio ejecutivo, área turística. Is located in Panama City, just 5 miles from Bridge of the Americas and 5.2 miles from Ancon Hill.

Scored out of 10, guest rating 9.2
Wonderful - What previous guests thought, 6 reviews
Price from
$95.20
1 night, 2 adults

AmazINN Places Casco Viejo Jacuzzi, Adults only

Casco Viejo, Panama City

Just a 3-minute walk from Canal Museum of Panama and 600 yards from Presidential Palace, AmazINN Places Casco Viejo Jacuzzi, Adults only features accommodations in Panama City with a garden.

J
Jaquelin
From
Guatemala
It was private, great location.
Scored out of 10, guest rating 9.2
Wonderful - What previous guests thought, 19 reviews
Price from
$165.19
1 night, 2 adults

Yc 701-B l Habitacion en av Balboa

Bella Vista, Panama City

4.7 miles from Bridge of the Americas in the center of Panama City, Yc 701-B l Habitacion en av Balboa offers accommodations with access to a sauna, spa facilities, and fitness room.

T
Terrance
From
United States
Excellent location. The rooftop views are amazing.
Scored out of 10, guest rating 9.0
Wonderful - What previous guests thought, 36 reviews
Price from
$88
1 night, 2 adults

AmazINN Places Casco Viejo relaxing Views and Sound of the Sea

Casco Viejo, Panama City

AmazINN Places Casco Viejo relaxing Views and Sound of the Sea is located in Panama City, just 2.8 miles from Bridge of the Americas and 3.6 miles from Ancon Hill.

E
Elena
From
Canada
Great location, yet quiet enough at night to sleep. Loved sitting on the balcony, watching all the people walking by and taking pictures of apartment as it is a gorgeous building. Plenty of space in the apartment for a family of 4. Pool table was a fun bonus. So many restaurants to choose from right out the front door. Very unique place to stay!
Scored out of 10, guest rating 9.1
Wonderful - What previous guests thought, 54 reviews
Price from
$184.23
1 night, 2 adults

AmazINN Places Casco Viejo Pool and Rooftop VIII

Casco Viejo, Panama City

AmazINN Places Casco Viejo Pool and Rooftop VIII offers accommodations in Panama City, 2.4 miles from Ancon Hill and 2.6 miles from Bridge of the Americas.

T
Theresa
From
Costa Rica
The room was spacious with high ceilings and tastefully decorated. There's a small kitchen and fridge along with 2 separate and equal sized bedrooms. Best sharing situation (there were 3 of us) that I have had a pleasure to stay. The location is perfect to explore the wonderful restaurants of Casco Viejo.
Scored out of 10, guest rating 9.2
Wonderful - What previous guests thought, 58 reviews
Price from
$162.85
1 night, 2 adults

Casa Duplex Privada con Piscina

Bella Vista, Panama City

Providing a garden, Casa Duplex Privada con Piscina features accommodations in Panama City. This property offers access to a balcony, free private parking, and free Wifi.

J
Jacquelyn
From
United States
This property hosted by Gerardo is a hidden gem within the city. Centrally located, clean,quiet and suited for a group stay. This house has all the features of home and Gerardo is so accommodating and accessible. I will stay here again ! Highly recommend if you are traveling with a group!!!
Scored out of 10, guest rating 9.6
Exceptional - What previous guests thought, 7 reviews
Price from
$415
1 night, 2 adults

Small loft at Casa Neuman, Casco Antiguo

Casco Viejo, Panama City

Small loft at Casa Neuman, Casco Antiguo is located in Panama City, just 2.4 miles from Bridge of the Americas and 7.6 miles from Rod Carew National Stadium.

N
Niraj
From
United States
Such a cool apartment Had everything we needed Nice entrance
Scored out of 10, guest rating 9.0
Wonderful - What previous guests thought, 70 reviews
Price from
$159
1 night, 2 adults

La Isabela Suites

Casco Viejo, Panama City

La Isabela Suites is a condo-hotel located in the heart of historic Casco Viejo, 656 feet from Presidential Palace and the waterfront and 984 feet from Canal Museum of Panama.

C
Cogan
From
Canada
This is a lovely apartment in the heart of the old town. The beds are super comfortable, the air conditioning is a lifesaver. I loved to sit in the private courtyard in the evening. La Isabela suites is in a great location. there are restaurants, shops and tourist sites all within walking distance..there is a little grocery store very close so it’s easy to cook in the well equipped kitchen. The staff at La Isabela suites are fabulous. They were very attentive and accommodating. Every suggestion they made for places to eat or visit was excellent. It is our second time here and we will definitely return. Andres and his team are wonderful.
Scored out of 10, guest rating 9.5
Exceptional - What previous guests thought, 93 reviews
Price from
$130
1 night, 2 adults

Nomada Republic Hotel Panama City

Bella Vista, Panama City

Nomada Republic Hotel Panama City is a condo hotel featuring rooms with free Wifi and air conditioning in the center of Panama City.

A
Ava148
From
Jamaica
Good location Friendly staff Comfortable bed Customer service top tier
Scored out of 10, guest rating 8.9
Excellent - What previous guests thought, 1,583 reviews
Price from
$79.52
1 night, 2 adults

La Cuadra By Wynwood House

Casco Viejo, Panama City

La Cuadra By Wynwood House enjoys a location in Panama City, 2.1 miles from Ancon Hill and 2.2 miles from Bridge of the Americas. Guests are welcome to go for a swim in the rooftop pool.

P
Patricia
From
Panama
The apartment, one bedroom, was big, beautiful decorated, with all you need for a nice and pleasant stay.
Scored out of 10, guest rating 8.0
Very Good - What previous guests thought, 104 reviews
Price from
$254.57
1 night, 2 adults
All vacation rentals in Panama City

Most booked vacation rentals in Panama City and surrounding area in the past month

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Popular with guests booking vacation rentals in Panama City

Scored out of 10, guest rating 8.9
Excellent - What previous guests thought, 1,583 reviews

Popular with guests booking vacation rentals in Panama City

Scored out of 10, guest rating 7.6
Good - What previous guests thought, 806 reviews

Popular with guests booking vacation rentals in Panama City

Scored out of 10, guest rating 7.6
Good - What previous guests thought, 661 reviews

Popular with guests booking vacation rentals in Panama City

Scored out of 10, guest rating 8.3
Very Good - What previous guests thought, 591 reviews

Popular with guests booking vacation rentals in Panama City

Scored out of 10, guest rating 8.3
Very Good - What previous guests thought, 749 reviews

Popular with guests booking vacation rentals in Panama City

Scored out of 10, guest rating 7.8
Good - What previous guests thought, 654 reviews

Popular with guests booking vacation rentals in Panama City

Scored out of 10, guest rating 7.7
Good - What previous guests thought, 668 reviews

Popular with guests booking vacation rentals in Panama City

Scored out of 10, guest rating 7.8
Good - What previous guests thought, 82 reviews

Popular with guests booking vacation rentals in Panama City

Scored out of 10, guest rating 5.8
Fair - What previous guests thought, 4 reviews

Vacation Rentals with swimming pools in Panama City and nearby

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Scored out of 10, guest rating 7.6
Good - What previous guests thought, 806 reviews

Scored out of 10, guest rating 8.3
Very Good - What previous guests thought, 591 reviews

Scored out of 10, guest rating 8.3
Very Good - What previous guests thought, 749 reviews

Scored out of 10, guest rating 7.8
Good - What previous guests thought, 654 reviews

Scored out of 10, guest rating 5.8
Fair - What previous guests thought, 4 reviews
Scored out of 10, guest rating 7.8
Good - What previous guests thought, 82 reviews

Scored out of 10, guest rating 7.9
Good - What previous guests thought, 332 reviews

Scored out of 10, guest rating 8.0
Very Good - What previous guests thought, 104 reviews

These vacation rentals in Panama City and nearby have options with free cancellation

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Nomada Republic Hotel Panama City

Calle 55 Este
Free cancellation options available
Scored out of 10, guest rating 8.9
Excellent - What previous guests thought, 1,583 reviews

Hotel Pensión Anduriña

Avenida Republica del Perú
Free cancellation options available
Scored out of 10, guest rating 7.6
Good - What previous guests thought, 661 reviews

Scored out of 10, guest rating 7.7
Good - What previous guests thought, 668 reviews

Corcho rooms

Calle Chiriqui Boquete
Free cancellation options available
Scored out of 10, guest rating 8.3
Very Good - What previous guests thought, 174 reviews

Scored out of 10, guest rating 8.8
Excellent - What previous guests thought, 410 reviews

Donovan Night Scene by Wynwood

Salsipuedes 1608
Free cancellation options available
Scored out of 10, guest rating 7.8
Good - What previous guests thought, 97 reviews

SERENADE Lodging Rooms

Calle 75 Este San Francisco
Free cancellation options available
Scored out of 10, guest rating 8.4
Very Good - What previous guests thought, 303 reviews

Highly rated vacation rentals in Panama City and nearby

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Scored out of 10, guest rating 7.0
Good - What previous guests thought, 202 reviews
Scored out of 10, guest rating 9.5
Exceptional - What previous guests thought, 93 reviews

Scored out of 10, guest rating 8.2
Very Good - What previous guests thought, 325 reviews

Scored out of 10, guest rating 9.0
Wonderful - What previous guests thought, 36 reviews

Scored out of 10, guest rating 8.0
Very Good - What previous guests thought, 88 reviews

Scored out of 10, guest rating 8.0
Very Good - What previous guests thought, 53 reviews

Scored out of 10, guest rating 8.8
Excellent - What previous guests thought, 65 reviews
Scored out of 10, guest rating 6.8
Pleasant - What previous guests thought, 30 reviews

FAQ about vacation rentals in Panama City

On average, a vacation rental in Panama City costs $90 per night (based on Booking.com prices).
The average price per night for a vacation rental in Panama City this weekend is $122 (based on Booking.com prices).
The average price of a vacation rental in Panama City this evening is $141 (based on Booking.com prices).
For vacation rentals in Panama City serving highly-rated breakfasts, try AmazINN Places Rooftop and Jacuzzi IV, AmazINN Places Hotel Boutique Casa Marichu, and SERENADE Lodging Rooms.
Casa Duplex Privada con Piscina, Amazing Loft With The Best View Of Casco Viejo!, and Grand Bay Tower have received great reviews from guests in Panama City about the views from these vacation rentals.

Vacation Rentals That Guests Love in Panama City

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Avg. price/night: $51.70
Scored out of 10, guest rating 8.4
Very Good - What previous guests thought, 303 reviews
The availability of the host who replied to my every query. She also allowed me to check in earlier. The room has all basic things for a short term stay and the small grocery store just across the road is very handy and welcomed. Wifi is good.
Guest review byMAIK GH
Solo traveler
Scored out of 10, guest rating 9.5
Exceptional - What previous guests thought, 180 reviews
Breakfast was not an option. This was a beautiful facility that felt like a Villa. Kitchen was large and available for cooking meals, beverages and snacks with refrigerator space too.
Guest review bySandra
Solo traveler
Avg. price/night: $105.79
Scored out of 10, guest rating 8.3
Very Good - What previous guests thought, 51 reviews
This is the best hotel/Airbnb I have ever stayed in and that says a lot. The staff were exceptionally accommodating, their communication was perfect through the apt and they could not have done more for me. Perfect for long term and short term stay. The location is phenomenal and I didn't have to deal with any noise at night. The air con was fabulous and I felt like a queen in this charming mix of old world charm with modern facilities.
Guest review bySilver
Solo traveler

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