Cleopatra is located opposite El Camisón Beach, in southern Tenerife. It features a spa, and an outdoor pool with a large sun terrace, surrounded by magnificent Roman columns and marble statues of gods. Each room at Hotel Cleopatra comes with a marble bathroom and opens onto a balcony or terrace. They also feature free Wi-Fi, satellite TV and a minifridge. At the Cleopatra Palace Hotel, guests can enjoy a rich buffet breakfast with national and international cuisine. During the day, guests can continue to enjoy the hotel's Pool Bar, with an expanded menu, and in the evening, the Hall Bar offers live music and a varied selection of cocktails ( both payment ). If Hotel Cleopatra guests wish to visit the Mediterranean Palace facilities, they can purchase a Day Pass at reception (only available if staying at the hotel). This includes access to the Mediterranean Palace solarium and pool, Splash Park, and Beach Volleyball. Children can join the Mediterranean Palace mini-club for an extra charge. The more athletic can use the Gym at the Mediterranean Palace for a fee. Access between hotels is restricted during the day, but at dinner time, after the pools close, access is fully open, so Cleopatra guests can enjoy the many dining options at Mare Nostrum Resort, such as "The Pier" Food Hall, Coal, Diabolo, Windsor, Palapa, or Hard Rock, where they will find a wide range of culinary offerings without having to leave the resort, paying the corresponding price at each point of sale. Safari Shopping Center, with plenty of shops and facilities is a 3-minute walk away. The hotel can be found 0.6 mi from Las Americas Golf Course. It is less than 9.3 mi from Tenerife Sur Airport.

Couples in particular like the location – they rated it 9.7 for a two-person trip.

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